GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9473555 | 1 | rs9463474 | chr6:49380199 | CENPQ | chr6:49431096-49460820:+ | -0.27 | -5.63 | 3.5E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463474 | chr6:49380199 | MUT | chr6:49398994-49431031:- | 0.28 | 5.53 | 5.97E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463475 | chr6:49380899 | CENPQ | chr6:49431096-49460820:+ | 0.28 | 5.61 | 3.79E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463475 | chr6:49380899 | MUT | chr6:49398994-49431031:- | -0.28 | -5.58 | 4.67E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463477 | chr6:49386446 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.66 | 2.91E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463477 | chr6:49386446 | MUT | chr6:49398994-49431031:- | 0.28 | 5.53 | 5.94E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9369898 | 1 | rs9463478 | chr6:49386564 | CENPQ | chr6:49431096-49460820:+ | -0.4 | -8.67 | 1.24E-16 | Homocysteine levels |
| BLCA | cis | rs9473555 | 1 | rs9463479 | chr6:49393275 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.66 | 2.91E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463479 | chr6:49393275 | MUT | chr6:49398994-49431031:- | 0.28 | 5.53 | 5.94E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463480 | chr6:49400795 | CENPQ | chr6:49431096-49460820:+ | -0.28 | -5.77 | 1.67E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9463480 | chr6:49400795 | MUT | chr6:49398994-49431031:- | 0.28 | 5.54 | 5.63E-8 | Folate pathway vitamin levels |
| BLCA | cis | rs2275426 | 1 | rs946529 | chr1:46485548 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.43 | 3.9E-10 | Body mass index |
| BLCA | cis | rs947211 | 1 | rs947211 | chr1:205752665 | RAB7L1 | chr1:205737115-205744610:- | 0.27 | 3.97 | 8.64E-5 | Parkinson's disease |
| BLCA | cis | rs9473555 | 1 | rs9473549 | chr6:49380020 | CENPQ | chr6:49431096-49460820:+ | -0.29 | -5.87 | 9.55E-9 | Folate pathway vitamin levels |
| BLCA | cis | rs9473555 | 1 | rs9473549 | chr6:49380020 | MUT | chr6:49398994-49431031:- | 0.26 | 5.03 | 7.58E-7 | Folate pathway vitamin levels |